In recent years, with the soaring number of infertility in our country (China) and the fully implementation of the second-child policy, as well as the publicity and attention of the media, celebrities and other groups on IVF technology, IVF technology has been well-known to the public. Facing the demand for fertility, more and more Chinese families are choosing test-tube to help produce healthy babies.
What is Test-tube Baby?
First Generation of IVF
Second Generation of IVF
Third Generation of IVF
Forth Generation of IVF
In Vitro Fertilization and Embryo Transfer (IVF-ET)
It is what we call conventional test tube baby, which is to take out the eggs and sperm of infertile couples in vitro. After the sperm is washed, the eggs are fertilized in the in vitro system and developed into embryos, and then the embryos are transplanted into the uterine cavity to achieve pregnancy. The fertilization of the egg in this process is close to the fertilization of the egg in a natural pregnancy.
Suitable Patient:
This kind of technique is mainly suitable for the woman's infertility, such as fallopian tube adhesion, obstruction, endometriosis, abnormal follicular development and ovulation.
Warm reminder: The success rate of IVF pregnancy depends on the quality of the technology. It is not that second generation is better than first generation as the technology is different and the applicable patient are also different. At present, the domestic restrictions on the third-generation test tube technology are still very strict in China, and the technology level is still a certain gap with overseas. Couples who have such need may choose overseas test tube babies.
Intracytoplasmic sperm injection (ICSI)
Intracytoplasmic sperm injection is to inject a single sperm into the oocyte plasma by micro-injection, so that the sperm and oocyte are passively combined and fertilized to form a fertilized egg and embryo transfer to achieve the goal of pregnancy.
Suitable Patient:
This kind of technology is mainly suitable for male infertility, such as severe oligoasthenospermia, irreversible obstructive azoospermia, spermatogenic dysfunction (excluding genetic defect diseases), sperm acrosome abnormalities, etc.. For embryos, ICSI is an invasive treatment, so it is limited to those who need it.
Warm reminder: The success rate of IVF pregnancy depends on the quality of the technology. It is not that second generation is better than first generation as the technology is different and the applicable patient are also different. At present, the domestic restrictions on the third-generation test tube technology are still very strict in China, and the technology level is still a certain gap with overseas. Couples who have such need may choose overseas test tube babies.
Preimplantation Genetic Diagnosis (PGD)
The third generation is the latest technology developed on the basis of the first and second generation IVF. The IVF process is the same as the first and second generation. The biggest difference is that before embryo implantation, doctors will use PGS (Preimplantation Genetic Screening) and PGD (Preimplantation Genetic Diagnosis) technology for genetic analysis, and select the best quality embryo for implantation. Help patients have the best offspring.
Suitable Patient：
This technique is mainly suitable for couples with special needs such as chromosomal abnormalities, infertility, family history of genetic diseases, prenatal and postnatal care. For example, hemophilia, thalassemia, etc. can all choose to use this technology.
Warm reminder: The success rate of IVF pregnancy depends on the quality of the technology. It is not that second generation is better than first generation as the technology is different and the applicable patient are also different. At present, the domestic restrictions on the third-generation test tube technology are still very strict in China, and the technology level is still a certain gap with overseas. Couples who have such need may choose overseas test tube babies.
Embryo Cytoplasmic Transfer Technology (GVT)
Also known as cytoplasmic replacement technology. Due to the aging problem of elderly female eggs, it is difficult to develop into embryos that can be used for transplantation, and the nucleus replacement is performed between the cytoplasm of young eggs and the nucleus of aging eggs. The nucleus of the aging egg and the cytoplasm of the young egg synthesize a new egg, which greatly increases the developmental potential of the egg and increases the possibility of pregnancy for older women. A baby born with this technology is also called a three-parent baby, which means that the baby has two mothers and one father.
Suitable Patient：
At present, the fourth-generation IVF technology has ethical controversy and has not been promoted clinically. Therefore, those hospitals that advertise that they can do fourth-generation IVF are deceptive, and I hope that the majority of patients will be clearly realized it.
Warm reminder: The success rate of IVF pregnancy depends on the quality of the technology. It is not that second generation is better than first generation as the technology is different and the applicable patient are also different. At present, the domestic restrictions on the third-generation test tube technology are still very strict in China, and the technology level is still a certain gap with overseas. Couples who have such need may choose overseas test tube babies.
The flowchart of the overseas Third Generation IVF
Going abroad 28 days for achieving fertility dream
Domestic counseling in formal service organization
Upon request, conducting body examination in China
Female：AMH (may conduct at anytime, no need fasting), Vaginal ultrasound(conduct at the third day or the seventh or eighth day of Menstruation, request to show the quality of all Oocyte), Six sex hormones (conduct at the second day of Menstruation)
Male：Semen analysis report